Ashley Koff, RD: GLP-1, Fasting and Midlife Weight Explained

Many women hit a weight plateau in perimenopause and assume it's about willpower, when the real issue is that the body isn't getting the physiological support it needs during hormonal change. After 40, eating less and pushing harder often puts the body into a protective mode, signaling it to conserve energy by storing fat.

We dive deeper into this in the latest Hello Hormones episode with Ashley Koff, RD. We also chat about why fasting often backfires in perimenopause, what actually changes when GLP-1 signaling lasts days instead of minutes, and why gut function, hydration, and stress signals decide whether the body feels safe enough to lose weight.

Ashley Koff, RD, is the founder of The Better Nutrition Program and the author of Your Best Shot: The Personalized System for Optimal Weight Health. She is a registered dietitian with over 30 years of experience across private practice, nutrition education, media, and consulting, and serves as Nutrition Course Director for IFMF.

What's Discussed:

• (02:59) How under-eating and over-exercising backfire after 40

• (03:21) GLP-1 as hormone replacement and why duration matters more than dose

• (11:17) Fasting in perimenopause: when it helps and when it hurts

• (19:32) Food variety, taste receptors, and GLP-1 signaling on the tongue

• (24:26) Stress, the vagus nerve, and why weight gain can be protective

• (29:29) The GLP-1 era, weight bias, and why judging bodies misses the point

• (43:19) What GLP-1 actually does in the body beyond appetite suppression

• (50:37) Can you stimulate GLP-1 naturally and what actually influences it

✍️ FREE GUIDES:

• Hormones 101 Cheat Sheet: www.drcarriejones.kit.com/hormones101

• The Perimenopause & Menopause Labs Test Checklist: www.drcarriejones.kit.com/labtestchecklist

• The Symptoms of The Perimenopausal Transition (WTF…) Ebook: www.drcarriejones.kit.com/perimenopausesymptom

• Which Stage of Perimenopause Am I In? Ebook: www.drcarriejones.kit.com/stagesofperimenopause

LETS CONNECT:

Dr. Carrie Jones: Website: www.drcarriejones.com Newsletter: www.drcarriejones.kit.com/newsletter IG: @dr.carriejones TikTok: @drcarriejones Youtube: @drcarriejones

Ashley Koff, RD: Website: www.thebetternutritionprogram.com Instagram: @ashleykoffapproved Ashley's Upcoming Book: ORDER HERE

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