Short Wave The secret history of DNA: Pus, fish sperm, life as we know it
Nov 11, 2021
Delve into the fascinating history of DNA, from its discovery by Friedrich Mischer to its foundational role in genetics. Learn how the iconic double helix isn’t what you’d see in our cells, and discover the mind-blowing compactness of DNA, fitting over six feet into a tiny nucleus. Explore the intricate dance of histone proteins that regulate gene expression, revealing how single cells transform into the complexity of multicellular life. It's a captivating journey through the molecule that defines life!
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Discovery of DNA
- Friedrich Miescher discovered DNA in 1871 while studying cells.
- He initially called it "nuclein" after finding it in the nucleus of pus and later fish sperm.
DNA's Simple Complexity
- Despite its complexity, DNA is made up of only four chemical letters: A, T, G, and C.
- Different combinations of these letters create the diversity of life.
DNA Packaging
- Stretched out, the DNA in a single human cell measures over six feet long.
- Efficient packing allows this enormous length to fit within a tiny nucleus.