Data in Biotech Jaidev Chakka on building the future of bioprinted medicine
Dec 26, 2025
Jaidev Chakka, a Principal Scientist at the University of Mississippi School of Pharmacy, dives into the world of 3D bioprinting and its revolutionary role in personalized medicine. He explains how custom scaffolds can regenerate bones and integrates gene therapy to enhance healing. The conversation touches on the balance between batch and continuous 3D manufacturing and the integration of AI for optimized drug delivery. Jaidev also discusses organoids as functional micro-organs, hinting at a future where on-demand drug production could transform healthcare.
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Post-Print Coating Adds Biological Function
- Coat high-temperature printed scaffolds post-print to add biological functionality without damaging biomolecules.
- Use polydopamine as a universal sticky layer to attach gene-delivery plasmid complexes to printed structures.
Strengths And Limits Of Printed Pharmaceuticals
- 3D printing excels at personalized multi-drug and dose-tailored tablets but lags mass production speeds.
- Printing one tablet in minutes limits scale; thousands-per-minute compression remains far faster for large-volume manufacture.
Favor Continuous Over Batch Printing
- Prefer continuous 3D printing processes over batch when possible to reduce contamination and improve consistency.
- Monitor continuous feeds and set stable parameters to avoid batch-to-batch variability and cleaning-related failures.