Big Ideas Lab Forensic Science Center (Part 2)
Jul 15, 2025
Audrey Williams, Director of the Forensic Science Center, and Carlos Valdes, Lead Chemist, dive into the critical world of forensic science tackling modern threats. They discuss the real-world implications of nerve agents like sarin, contrasting Hollywood's portrayal with scientific reality. The duo reveals their innovative work on developing antidotes for nerve agents and fentanyl, including a donut-shaped molecule designed to neutralize the deadly opioid. Their research also includes detecting hazardous pesticides in cannabis, showcasing the diverse applications of their expertise in national security and public health.
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Molecules Reveal Origins
- Chemical forensics can link agents to origins by studying impurities and molecular traces.
- That trace-level chemical information helped attribute sarin and sulfur mustard use in Syria and supported global action.
Dual Mission: Casework And R&D
- The Forensic Science Center balances operational casework with R&D into WMD countermeasures.
- That dual mission lets LLNL both respond to real cases and develop new detection and mitigation tools.
Unique Mixed-Hazard Capability
- The FSC can accept and analyze truly mixed-hazard samples containing chemical, biological, radiological, explosive, or nuclear agents.
- Their detection limits often reach parts-per-trillion, enabling extremely sensitive identification across hazards.


