The Cribsiders S7 Ep164: Notes on Neuroblastoma
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Jan 14, 2026 Dr. Brittany Greene, a pediatric oncologist and bioethicist at Seattle Children's Hospital, dives into the complexities of neuroblastoma in a captivating discussion. She shares insights on early symptoms like periorbital bruising and the importance of differentiating between various abdominal masses. Brittany discusses the significance of staging and the nuanced treatment strategies based on risk groups. She also highlights disparities in outcomes and emphasizes the value of effective communication with families. A must-listen for anyone in pediatric care!
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NICU Experience Changed Her Communication
- Brittany Greene shared that having twins in the NICU surprised her emotionally and changed how she communicates with families.
- That experience made her value communication from all team members, not just physicians.
Expedite Inpatient Workup And Coordinate Procedures
- When neuroblastoma is suspected, admit patients frequently so the multidisciplinary workup (labs, MIBG, marrow, biopsy, central line) can be completed urgently.
- Coordinate procedures (biopsy, marrow, central line) to minimize anesthesia and speed time-to-treatment.
Age Dictates Tumor Behavior
- Neuroblastoma displays a spectrum from spontaneous regression in infants to aggressive metastatic disease in older children.
- Age and tumor biology strongly influence risk stratification and management decisions.