
Spotlight on Migraine® Breaking Down Your Migraine Preventive Options: Medications, Vitamins & Devices
Apr 2, 2026
Dr. Jessica Ailani, neurologist and director of the MedStar Georgetown Headache Center, breaks down migraine prevention tools. She covers lifestyle foundations, vitamins versus when to try prescription meds, CGRP-targeted options, Botox for chronic migraine, neuromodulation devices, combining treatments, and approaches for menstrual migraine.
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Choose Regular Meals And Protein
- Focus dietary efforts on regular meal timing and protein at each meal rather than rigidly eliminating perceived triggers.
- Avoid over-restricting foods and stay hydrated with water rather than sugary drinks to reduce stress and self-blame around attacks.
Start With B2 And Magnesium
- Try simple supplements before prescription preventives: riboflavin (B2) and magnesium have supportive evidence.
- Use them for a few months; if ineffective or if you have chronic migraine, consider moving to medication options.
CGRP Treatments Calm The Migraine Brain
- New migraine-specific treatments target the protein CGRP to reduce brain irritability and attack frequency.
- Options include monthly self-injections, daily/oral G‑pats, and an office infusion every three months offering flexible choices.

