BMJ Best Practice Podcast Generalised seizures in adults
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May 29, 2025 Join Daniel Winkel, Assistant Professor of Neurology at Emory University, as he dives into the world of generalized seizures. With 45.9 million people living with epilepsy globally, the discussion highlights the serious implications of recurrent unprovoked seizures. Discover different seizure types beyond tonic-clonic, the essential role of accurate diagnosis, and how individual factors affect treatment choices. Daniel also examines the interplay between antidepressants and seizures, emphasizing timely interventions and the need for better research in this vital area.
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Role of Blood Tests and Genetics
- Blood tests have no definitive marker for epilepsy but help identify seizure triggers.
- Genetic testing is becoming important for understanding and diagnosing generalized epilepsies.
Key Features Suggesting Seizures
- Consider tongue biting, incontinence, and postictal sleepiness as clues to confirm seizures.
- Gather a rich history to differentiate seizures from other mimics like syncope.
Refer Generalised Seizures to Neurologists
- Always refer suspected generalized seizure cases to a neurologist for accurate diagnosis.
- Correct classification affects drug choice and potential surgical or device treatment options.