Possible

The power of AI, from curing cancer to ballot boxes

41 snips
Dec 17, 2025
Siddhartha Mukherjee, a Pulitzer Prize-winning oncologist and the mind behind Manas AI, dives deep into the transformative role of AI in medicine. He highlights breakthroughs in cancer immunotherapy, including engineered T-cells that tackle previously unsolvable cases. The conversation extends to AI's potential in drug discovery, creating a 'molecular oracle' for new treatments. They also explore Silicon Valley's evolving culture, advocating for technology that prioritizes humanity and truth, especially as AI influences public discourse and political opinion.
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INSIGHT

Early Detection Creates New Dilemmas

  • Early detection technologies like blood tests and full-body scans have transformed possibilities.
  • The key question now is what to do when we find early or incidental signals.
ANECDOTE

Founding Manus To Be AI-Native

  • Reid Hoffman, Ujwal Singh, and Siddhartha Mukherjee co-founded Manus AI to apply AI to drug creation.
  • Manus focuses on AI-native drug discovery, using models to design molecules that block cancer targets.
INSIGHT

AI As Molecular Oracle

  • Manus treats AI as the creative engine for molecular design, not merely data management.
  • They aim to place atoms with atomic precision to block protein activity driving cancer.
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