
Possible The power of AI, from curing cancer to ballot boxes
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Dec 17, 2025 Siddhartha Mukherjee, a Pulitzer Prize-winning oncologist and the mind behind Manas AI, dives deep into the transformative role of AI in medicine. He highlights breakthroughs in cancer immunotherapy, including engineered T-cells that tackle previously unsolvable cases. The conversation extends to AI's potential in drug discovery, creating a 'molecular oracle' for new treatments. They also explore Silicon Valley's evolving culture, advocating for technology that prioritizes humanity and truth, especially as AI influences public discourse and political opinion.
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Early Detection Creates New Dilemmas
- Early detection technologies like blood tests and full-body scans have transformed possibilities.
- The key question now is what to do when we find early or incidental signals.
Founding Manus To Be AI-Native
- Reid Hoffman, Ujwal Singh, and Siddhartha Mukherjee co-founded Manus AI to apply AI to drug creation.
- Manus focuses on AI-native drug discovery, using models to design molecules that block cancer targets.
AI As Molecular Oracle
- Manus treats AI as the creative engine for molecular design, not merely data management.
- They aim to place atoms with atomic precision to block protein activity driving cancer.




