Rena Malik, MD Podcast

Do Supplements Like Selenium and Vitamin E Help or Harm Prostate Health?

19 snips
Feb 6, 2026
Dr. Scott Eggener, urologic oncologist and UCLA chair focused on prostate cancer research and reducing overdiagnosis. They unpack prevention, lifestyle and exercise effects. They debate supplements like selenium and vitamin E and review screening strategies, PSA interpretation, MRI and biomarkers. Treatment choices, surveillance for low-grade cancer, and emerging tech like focal therapy and AI are also explored.
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INSIGHT

Prostate Cancer: High Prevalence, Low Lethality

  • Most men diagnosed with prostate cancer will not have long-term problems, yet it remains the second-leading cause of cancer death in US men.
  • Knowing your individual risk and screening appropriately balances preventing deaths while avoiding overdiagnosis.
ADVICE

Prioritize Lifestyle Over Pills

  • Eat real food, limit alcohol, and exercise regularly to lower prostate cancer risk.
  • Try high-intensity interval training three times a week if interested, as small trials showed PSA and biopsy benefits.
INSIGHT

Supplements Can Harm, Not Help

  • Observational links between supplements and lower prostate cancer risk often fail in randomized trials.
  • The SELECT trial found vitamin E increased prostate cancer risk and selenium raised diabetes risk.
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