Pre PACES Podcast #35 Parkinsonism
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May 22, 2022 Dr. Iain Wilkinson, a consultant geriatrician and movement disorders expert, dives into the nuances of Parkinsonism. He explains the key differences between Parkinsonism and Parkinson's disease, outlines essential examination techniques, and discusses differential diagnoses. Iain also covers management strategies, including medication options and the importance of multidisciplinary support. Plus, tune in for Iain's fun quiz on modern folk music, showcasing his hidden talent and passion for the genre!
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Parkinsonism Versus Parkinson's Disease
- Parkinsonism is a clinical cluster defined by bradykinesia plus tremor and/or rigidity.
- Parkinson's disease sits on a spectrum with variable onset, tremor dominance, and progression.
Alpha-Synuclein And Braak Progression
- Parkinson's pathology arises from alpha-synuclein aggregation forming Lewy bodies and causing dopamine loss.
- Braak staging explains early non-motor features (anosmia, REM sleep disorder) before motor signs appear.
Begin With Focused Observation
- Start neurological exam by observing the patient and the bed area for mobility aids and medications.
- Look for resting tremor and reduced facial expression before touching the patient.