Accenture AI Leaders Podcast AI Leaders Podcast #80: Human in the Lead: Redesigning Agency and Trust in AI
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Feb 20, 2026 Simon Nazarian, Chief Digital & Technology Officer at City of Hope, leads digital transformation and AI in healthcare. He discusses shifting decision rights as machines join the workforce. He explores designing AI that expands human judgment, embedding AI into clinical workflows, and turning pilots into living platforms. He also covers governance as a partner and rethinking roles for the GenAI era.
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Gen AI Demands Rearchitecting Decision Rights
- Gen AI forces leaders to redesign decision architecture, not just add technology as an overlay.
- Agency means right to decide, obligation to act, and accountability for outcomes, which current centralized permission models break when machines enter workforces.
Provide Explainability And Guardrails Not Just Scores
- Give clinicians context, not just predictions, and embed policy guardrails so teams can act safely at speed.
- City of Hope exposes factors driving risk scores and automates ethical checks to let frontline teams decide with confidence.
AI Becomes A Traceable Decision Actor
- Treat deployed AI as a decision actor with traceable accountability rather than mere software.
- Track who trained models, what data shaped them, and which policies were active when a decision occurred to preserve trust.