The Psychedelic Podcast

Can Ketamine Help Benzodiazepine Withdrawal? - Melissa Bond & Dr. Amy de la Garza

Apr 6, 2026
Dr. Amy de la Garza, a family and addiction medicine physician blending functional care and ketamine‑assisted approaches. Melissa Bond, a journalist and poet who wrote Blood Orange Night about benzodiazepine dependence. They discuss how benzodiazepines reshape the nervous system, why withdrawal can be prolonged and destabilizing, challenges of long tapers, and the emerging use and cautions of low‑dose ketamine as a supporting tool.
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INSIGHT

Benzodiazepines Are For Short Acute Use Only

  • Amy de la Garza emphasizes benzodiazepines are only appropriate short-term, ideally 7–10 days, because tolerance and withdrawal can emerge within a week.
  • In practice clinicians default to benzos for quick relief due to time-limited visits, not because they're ideal for chronic insomnia.
ADVICE

Avoid Chronic Benzo Prescriptions Use Safer Alternatives

  • Avoid chronic benzo prescribing; choose non-dependent alternatives and use lifestyle interventions first for chronic insomnia.
  • Use benzodiazepines only for acute episodes or brief bridging while initiating other treatments.
ANECDOTE

Mid-Taper Collapse Revealed Ongoing Withdrawal

  • Melissa describes an episode where her legs “went liquid” picking up her one-year-old, prompting fear of a brain tumor or MS.
  • Research later matched her symptoms to benzodiazepine withdrawal while she was still taking the drug.
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