The Melissa Ambrosini Show 698: Live Longer & Feel Better: The Real Secrets to Longevity | Chris Burres
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Apr 17, 2026 
Chris Burres, scientist-entrepreneur behind MyVitalC and ESS60, and author of Live Longer and Better. He discusses fasting, sleep, mindset and stress regulation. He explains mitochondrial-focused compounds, practical daily routines, breathwork and micro-habits. He also covers peptide topicals, who should avoid certain supplements, and his research plans.
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Chris Uses Weekly 24-Hour Fasts For Autophagy
- Chris Burres fasts weekly, doing a 24-hour fast on Mondays and sometimes drinks coffee with collagen that technically breaks a fast.
- He notes fasting aims for autophagy and also helps control hunger differently than calorie-counting diets.
Displace Negative Thoughts With Short Mantras
- Replace negative thoughts by deliberately substituting a short positive mantra repeatedly.
- Burres has used a teenage habit of repeating phrases like 'I'm healthy; I'm motivated' to displace ruminating negative thoughts.
Use Small Nonnegotiables As Habit Fallbacks
- Build tiny, nonnegotiable habits and a fallback routine to manage stress and stay consistent.
- Burres suggests a minimal fallback (e.g., 50 pushups/sit-ups/squats or a 10-minute walk) to maintain habit momentum.
