Tryp Rapport Episode 105 - Ketamine Therapy with Amy
Feb 1, 2026
A deep dive into therapeutic ketamine: training paths and why practitioners choose it. Vivid descriptions of dissociation, visions, and session length variability. Practical differences between troches and IM dosing plus administration tips. Safety topics including bladder risk, screening, meds, adolescent research, and how to vet clinics.
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First IM Trip Was Visual Grief Work
- Amy's first IM ketamine trips were visual and dissociative with stars, brown flowing visuals, and a brief dragon appearance.
- She felt body-disconnection but remained conscious, found self-acceptance, and experienced in-and-out streams of awareness rather than sustained narrative.
Troche Peak Mirrors IM But Comes Slower
- Troches produce a slower on/off curve but can reach similar peak effects as IM dosing according to Amy.
- IM is better for time management and clinics that need multiple sessions per day, while troches feel gentler overall.
Hold Troches 12 Minutes And Use Antiemetic
- Do require troches to be held in the mouth for 12 minutes or follow prescriber guidance and prepare for taste and potential nausea.
- Amy times guided meditations during that 12-minute period and gives Zofran beforehand to prevent nausea.