Menopause & Heart Disease Risk: The Lipid Changes Doctors Miss (LDL, Triglycerides, ApoB, Lp(a) + What To Do)

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This podcast episode is sponsored by Complete Medicine and HeyHealthy.

Welcome back to Endocrine Matters. I’m your host, Dr. Arti Thangudu, board-certified endocrinologist, menopause society certified practitioner, and founder of Complete Medicine, where we care for high-achieving women living with obesity, prediabetes, diabetes, thyroid disease, and metabolic conditions.

Menopause & Heart Disease Risk: The Lipid Changes Doctors Miss (LDL, Triglycerides, ApoB, Lp(a) + What To Do)

On Endocrine Matters, Dr. Arti Thangudu joins endocrinologists Dr. Munira Mehta and Dr. Vidhya Illuri and dietitian Ana Mendez to discuss the often-overlooked rise in cardiovascular risk during the menopausal transition, when LDL, total cholesterol, ApoB, and triglycerides increase most sharply from about one year before to one to two years after the final menstrual period, independent of age and environmental factors. They explain how estrogen loss shifts lipids toward a more atherogenic profile, how HDL quantity and function can change, and why triglycerides above 200 predict worse cardiovascular health while goals are typically fasting levels under 150. They review who may need earlier screening (premature ovarian insufficiency, PCOS, early menopause, strong family history, some ethnic groups), lifestyle strategies (Mediterranean/DASH, fiber, fatty fish), and add-on tests like ApoB and Lp(a), plus coronary calcium scoring and statins for risk-based treatment.

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