BackTable Vascular & Interventional Ep. 20 Pressure-Directed Therapy in TACE with Dr. Justin Lee and Dr. Terence Gade
Jan 20, 2018
Dr. Justin Lee, an experienced interventional radiologist from Florida Interventional Specialists, and Dr. Terence Gade, an assistant professor at the Hospital of the University of Pennsylvania, dive into the complexities of pressure-directed infusion for transcatheter arterial chemoembolization (TACE). They discuss the clinical nuances of using TACE versus Y90, share insights on hydrostatic barriers to drug delivery, and explain how their techniques enhance tumor uptake with anti-reflux catheters. Expect practical tips and cutting-edge research blended with real-world applications!
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Building Advanced IO In The Community
- Justin moved from academia to build an advanced IO program in Sarasota and introduced Surefire into trials.
- He values keeping complex care local so patients avoid travel to tertiary centers.
Clinical Research Split And Practice Contrast
- Terrence describes his split role: 30% clinical, 70% research, and co-directing the Piggy Lab.
- He contrasts CAM-TACE using lipiodol with DEB-TACE practices across Penn and the VA.
Ischemia Creates Targetable Vulnerabilities
- Embolization induces ischemic stress responses that create targetable vulnerabilities independent of mutations.
- Hyperpolarized metabolic imaging reveals cell populations invisible to conventional scans.