Patrick Holford: Simple Wisdom for a Healthy Life Anti-Age Your Brain Think Tank
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Jun 14, 2024 Dr Konrad Kowalski, analytical chemist who developed a dry blood spot glutathione test. Dr Filip Van Hulle, CoQ10 and mitochondrial specialist. Associate Professor David Vauzour, researcher on brain aging and antioxidants. They discuss glutathione measurement and decline, CoQ10/ubiquinol and statin interactions, dietary antioxidants and recycling, plus nutrition, supplements and mitochondrial support for brain aging.
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Take Ubiquinol To Support Mitochondria
- Supplement ubiquinol (e.g., 100 mg/day) to support mitochondrial ATP production and act as a fat-soluble antioxidant.
- Ubiquinol may increase mitochondria number and spare glutathione by reducing oxidative load.
Counter Statin Effects With CoQ10
- If you take statins, supplement CoQ10 because statins inhibit the same enzyme (HMG-CoA reductase) that synthesises ubiquinol.
- Consider 100 mg ubiquinol daily to reduce statin-associated muscle symptoms and preserve cellular CoQ10.
Don't Mix Bananas With Berries In Smoothies
- Avoid blending banana with polyphenol-rich berries in smoothies because banana polyphenol oxidase can inactivate berry antioxidants.
- Combine berries with other fruits that don't contain the oxidising enzyme to preserve anthocyanin benefits.