#275 Jay Yu - Nano Nuclear Technology and the Future of American Energy

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Jan 29, 2026

Jay Yu, DeepTech and NuclearTech entrepreneur who leads NANO Nuclear Energy and LIS Technologies. He discusses microreactors for military bases, islands, disaster relief, and datacenters. He covers laser uranium enrichment, domestic fuel security, regulatory timelines, and the race with China. Short, fast-paced conversation about building teams, raising capital, and scaling advanced nuclear technologies.

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ANECDOTE

From Skepticism To Top IPO

Nano Nuclear began as an improbable idea led by outsiders, and hedge funds bet against them.
Despite skepticism, Jay and his team worked relentlessly and achieved the top IPO performance of 2024.

INSIGHT

Microreactors Democratize Power

Microreactors unlock use cases that large reactors cannot: island grids, disaster response, remote communities, and military deployment.
Transportable baseload power can democratize energy and enable services like desalination and hospitals.

ADVICE

Make Reactors Factory‑Built And Modular

Design reactors that are factory‑produced and modular to scale like modern manufacturing.
Prioritize walkaway‑safe fuels (TRISO) and modular Lego‑style deployment to ensure resilience and mass production.

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Jay Yu is a prominent DeepTech and NuclearTech entrepreneur with a Wall Street capital markets background. Driven by a vision to make energy more accessible, affordable, and sustainable worldwide, he currently serves as Executive Chairman & CEO of LIS Technologies Inc. (LIST) and Founder & Chairman of NANO Nuclear Energy Inc. (NASDAQ: NNE).

LIS Technologies is the only U.S.-origin and patented laser uranium enrichment technology company, delivering a revolutionary, energy- and cost-efficient approach that is set to redefine nuclear fuel industry standards while also producing medical and stable isotopes; including silicon-28 critical for AI and quantum computing.

NANO Nuclear Energy Inc. (NNE) is the first publicly listed, vertically integrated advanced nuclear micro modular reactor company in the United States. Under Jay Yu’s leadership, NNE acquired one of the highest Technology Readiness Level (TRL) and patented microreactor designs in development, achieved a market capitalization exceeding $3 billion, raised over $600 million in just a year and a half, and earned the title of Wall Street’s Cinderella story of 2024 as the #1 Top IPO Performer.

Leading a world-class team of nuclear engineers, former national leaders in military and policy, U.S. Department of Energy experts, national laboratory veterans, and regulatory specialists, Jay is developing smaller, simpler, and safer advanced nuclear microreactors. He brings deep expertise in corporate structuring, capital fundraising, and recruiting top-tier talent while passionately building strategic relationships and creating lasting value for partners and stakeholders. In 2021, Jay Yu was honored as one of The Outstanding 50 Asian Americans in Business; the highest recognition in the U.S. AAPI community.

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Jay Yu Links:

X - https://x.com/nano_nuclear

IG - https://www.instagram.com/nanonuclear

YT - https://www.youtube.com/@nanonuclearenergy

NANO Nuclear - https://nanonuclearenergy.com

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