
What's Your Number? Is AI Drug Discovery Finally Here? - with Daphne Koller
Feb 4, 2026
Daphne Koller, AI researcher and entrepreneur who leads Insitro and co-founded Coursera, joins to discuss machine learningādriven drug discovery. She talks about why drug discovery fails at high rates. She explains how AI can uncover new biological targets, the need for biologics capabilities, and why Israelās talent ecosystem matters for AI and biology.
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Train People To Work With AI
- Daphne Koller advises to teach people how to ideate with AI and break problems into computable tasks.
- She urges deliberate education in collaborating with machines rather than assuming people will pick it up.
Talent Identification Shapes Innovation
- Daphne observes talent exists globally but nations differ in identifying and nurturing it.
- She credits Israel's military and U.S. education for mechanisms that cultivate high-potential people.
Why Drug Discovery Fails
- Daphne Koller says drug discovery fails because we treat patients as experiments and lack deep biological understanding.
- She argues measuring biology at scale plus AI can reveal actionable, high-conviction targets.

