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Coffee: Caffeine Plus Polyphenols
- Coffee's benefits likely stem from both caffeine and polyphenols such as chlorogenic acids. These compounds enhance cerebral blood flow, reduce neuroinflammation, and may be neuroprotective.
Flavonoids Boost Blood Flow And BDNF
- Flavonoid-rich foods (berries, cocoa, citrus) show short-term vascular and cognitive boosts. Acute blood-flow effects may translate to long-term protection via sustained BDNF and synaptic plasticity.
Supplement Vitamin D If Deficient
- Target vitamin D supplementation to people who are deficient rather than blanket high doses. Maintain steady, physiologic vitamin D levels long-term rather than using large bolus doses late in life.