The Top Line

How physiology powers biotech innovation (Sponsored)

8 snips
Mar 2, 2026
Sue Bodine, a professor at Oklahoma Medical Research Foundation and president-elect of the American Physiological Society, discusses how physiology links genes to whole-body function. She talks about its role in drug discovery, making wearable data meaningful, and why AI needs biological context. She also highlights efforts to raise physiology’s profile amid funding risks.
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INSIGHT

Physiology Is The Translation Engine

  • Physiology links genes and molecules to whole-body function and clinical outcomes.
  • Sue Bodine explains physiology as the translation engine that validates targets and shows whether drugs work in whole organisms.
ADVICE

Include Physiologists In Wearable Design

  • Integrate physiologists into wearable and sensor projects to standardize data collection and interpretation.
  • Sue Bodine says physiologists ensure real physiological signals are collected and correctly interpreted for trials and personalized care.
INSIGHT

AI Requires Physiological Context

  • AI needs physiological context to produce clinically meaningful predictions rather than optimizing easy-to-measure noise.
  • Sue Bodine warns that without physiology, models predict measurable artifacts not true biological responses.
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