Dr. Jockers Functional Nutrition

The Truth About Cellular Inflammation and Chronic Disease

Mar 26, 2026
They unpack how persistent cellular inflammation starts and the molecular triggers that keep it rolling. Learn about NF‑kB’s runaway inflammation, DAMPs and PAMPs, and the cell danger response. Hear why metabolic flexibility, oxidative stress, and omega fat balance matter. Practical lifestyle, toxin-reduction, nutrient and supplement approaches for calming chronic inflammation are highlighted.
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INSIGHT

Inflammation Is A Protective Survival Mechanism

  • Inflammation is a life-saving response designed to prevent infections after trauma.
  • David Jockers explains ancestral context: inflammation protected against wounds leading to systemic infections that historically killed more people than battle injuries.
ANECDOTE

Ancestral Examples Explain Why Inflammation Is Vital

  • Jockers uses ancestral examples like falling from trees or spear wounds to illustrate why inflammation evolved.
  • He emphasizes infections after injury (pneumonia, encephalitis) historically killed more people than battle wounds.
INSIGHT

How DAMPs PAMPs Trigger The NFKB Alarm

  • DAMPs and PAMPs trigger pattern recognition receptors that activate NFKB and amplify inflammation.
  • Jockers names receptors like toll-like and NOD-like receptors and describes NFKB as a self-amplifying alarm that can cause collateral tissue damage.
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