Development and Research How (not) to waste a billion dollars (on your clinical trial) — with Meri Beckwith
15 snips
May 20, 2025 
Meri Beckwith, Founder of Lindus Health, shares her unique perspective as a clinical trial patient and venture capitalist. She reveals why clinical trials lag behind in technology adoption. Meri discusses unexpected factors, like a flooded supply closet, that can lead to billion-dollar failures. She highlights the need for innovative patient recruitment and streamlined operations to enhance trial integrity. Lastly, she critiques traditional practices and advocates for adaptive methodologies to revolutionize drug development and improve patient engagement.
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Biotech Founders Lose Control
- Biotech founders experience far greater dilution and less control compared to tech founders.
- This difference stifles ambition and leads to fewer generational biotech successes.
Vicious Cycle Crushing Ambition
- The clinical trial process is so slow and costly that it discourages risk-taking and innovation.
- The industry suffers a vicious cycle where lack of ambition sustains inefficiency.
Run Adaptive Iterative Trials
- Use adaptive trials with multiple arms to iterate formulations and patient populations.
- This approach improves drug effectiveness and probability of success.