
Capital Allocators – Inside the Institutional Investment Industry Josh Wolfe & Brett McGurk – Venture, Geopolitics, and the Next Frontier (EP.476)
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Dec 8, 2025 Josh Wolfe, co-founder of Lux Capital and expert in AI, biotech, and defense, teams up with Brett McGurk, former U.S. national security advisor, to explore the intersection of venture capital and geopolitics. They discuss the evolving venture landscape, emphasizing the divide between small funds and mega firms. Brett shares insights from his time in public service, highlighting geopolitical risks like AI militarization and nuclear threats. Together, they delve into the future of technology, including maintenance opportunities and the potential of biology and robotics.
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Comp Structure Drives Sourcing Advantage
- Structure compensation to reward sourcing, deal-winning, and firm-building activities.
- Keep the organization flat and prize unique contributions from each partner.
From Baghdad To Four White Houses
- Brett described joining multiple administrations and going to Baghdad in 2004, which shaped his worldview.
- That experience taught him how crises recalibrate strategy and resource alignment in practice.
Geopolitics: New Domains And Rising Risks
- Geopolitical risks include counterterrorism, rising nuclear risk, and military AI applications.
- Space will be geopolitically contested with collaboration and near-peer competition shaping strategy.

