SpreadLove In Organizations - Healthcare Leadership

AI, Leadership, Love – Dimitrios Skaltsas

Oct 2, 2025
Dimitrios Skaltsas, CEO and co-founder of Intelligencia AI, shares his inspiring journey from studying law in Greece to pioneering AI in healthcare. He discusses the decline in R&D productivity and how AI can transform risk assessment in drug development. Dimitrios highlights the importance of blending human intuition with data-driven insights, emphasizing AI's role as a decision-support tool. He also reflects on the connection between creativity and leadership, advocating for caring leadership practices and a focus on prevention in healthcare.
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ANECDOTE

Nonlinear Path To Life Sciences

  • He recounts switching from law to engineering and then consulting at McKinsey before focusing on life sciences.
  • Those shifts were driven by a desire for social impact and an attraction to the people and pace of life sciences.
INSIGHT

Quantifying R&D Risk With AI

  • R&D productivity has declined and risk assessment in drug development lacked scientific rigor.
  • Intelligencia uses ML and patent intelligence to quantify probability of success and triangulate decisions for portfolio management.
ADVICE

Model Phase Transitions Explicitly

  • Train models to predict technical and regulatory phase transitions using engineered features and historical data.
  • Use model outputs to differentiate programs and provide explicit probabilities to support portfolio decisions.
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