Conan O’Brien Needs A Friend Conan Vs. Edibles Part I
47 snips
Apr 16, 2026 Conan confronts a box of edible cannabis and debates whether to try them. Staff explain energy, chill, CBD and THCV varieties and give dosing and timing tips. Conversations cover personal edible stories, productivity worries, and plans to test and report back.
AI Snips
Chapters
Transcript
Episode notes
Start Low Wait Long With Edibles
- Start very low and wait before increasing dose when trying edibles for the first time.
- Conan's team recommends beginning with 2.5–5 mg, wait ~30+ minutes, then only step up if needed to avoid anxiety or overshoot.
Pick Edibles By Cannabinoid Effect Not Hype
- Different cannabinoids produce distinct effects so choose products by desired outcome rather than brand hype.
- Sona distinguishes CBD for mellowing/pain relief, THCV for pep, and other formulations marketed as sleep, chill, or energy.
Anxiety Means Start Smaller Than Others Suggest
- If you're anxious, start with a smaller dose because too much can increase anxiety instead of reducing it.
- Eduardo and others caution Conan to begin with half or a full 2.5–5 mg dose rather than jumping to 10 mg.