Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas 251 | Rosemary Braun on Uncovering Patterns in Biological Complexity
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Sep 25, 2023 In this conversation, Rosemary Braun, an associate professor of molecular biosciences, unpacks the mysteries of biological complexity. She discusses how biological organisms, despite their seemingly chaotic parts, function seamlessly. Braun highlights the intersection of machine learning with biological research, showcasing how vast datasets shed light on gene expression and circadian rhythms. The dialogue also touches on the challenges of interpreting genetic information and the fascinating ways our internal clocks affect health and metabolism.
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Theoretical Biology
- Rosemary Braun is a theoretical biologist with a physics background.
- She transitioned to biology due to her interest in complex systems.
Omics Data
- Omics refers to various high-throughput biological data types (genomics, transcriptomics, proteomics).
- These technologies enable studying gene expression, variations, and protein abundances.
MicroRNA and System Control
- MicroRNAs are small molecules that regulate gene expression.
- A single microRNA can target numerous mRNAs, enabling systems-level control.