Research To Practice | Oncology Videos Multiple Myeloma | Oncology Today with Dr Neil Love: BCMA-Directed Therapies for Multiple Myeloma
Sep 29, 2022
48:10
Featuring an interview with Dr Amrita Krishnan, including the following topics:
- Case: A woman in her early 60s who presents with renal failure and receives CyBorD for multiple myeloma (MM) (0:00)
- Dyspnea associated with carfilzomib; ocular toxicity with belantamab mafodotin (6:26)
- Efficacy, tolerability and sequencing of belantamab mafodotin for MM; myths and misperceptions (10:33)
- Case: A man in his early 70s who presents with back pain and compression fractures; efficacy of bispecific antibodies compared to chimeric antigen receptor (CAR) T-cell therapy (17:40)
- Emerging data with the GPRC5D-targeted bispecific antibody talquetamab; similarities and differences in the pharmacology of BCMA-targeted bispecific antibodies for MM (25:31)
- Case: A man in his mid 50s who presents with severe back pain and an L5 mass (30:22)
- Diagnosis and management of cytokine release syndrome, neurotoxicity and infectious complications with CAR T-cell therapy (35:05)
- Future roles of bispecific antibodies, CAR T-cell therapy and transplantation in the treatment of MM; eligibility criteria for patients to receive CAR T-cell therapy (44:06)