The Dr. Layne Norton Podcast AMA 04 - Cortisol, Seed Oils, Insulin, Biggest Loser and More
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Apr 27, 2026 A rapid-fire Q&A covering cortisol and dieting myths, sucralose and gut microbiome questions, and whether seed oils drive inflammation. Discussion of insulin, high-glycemic carbs, and what overfeeding studies actually show about fat storage. Practical takes on youth resistance training, creatine dosing by body mass, concurrent cardio and strength, and reactions to The Biggest Loser documentary.
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Seed Oils Outperform Saturated Fat In Trials
- Don't vilify seed oils; compare them by calories and against saturated fat in trials.
- Randomized human trials show seed oils (linoleic acid) lower inflammation, liver fat, and heart disease risk versus equivalent saturated fat calories.
Calories Beat Insulin For Fat Gain
- Equate calories before blaming carbs or insulin for body-fat changes.
- Controlled feeding trials show no body-composition difference between high and low glycemic diets when calories and protein match; GLP-1 drugs raise insulin yet reduce weight via appetite suppression.
Natural Isn't Automatically Better
- The naturalistic fallacy misleads dietary choices; 'natural' doesn't equal healthy.
- Ultra-processed foods harm because they're energy dense, less satiating, and cheaper, not because they're man-made per se.