The a16z Show

Journal Club: Therapeutic Video Game on Trial

Jun 28, 2020
Join Justin Larkin, a partner at Andreessen Horowitz’s bio fund and former entrepreneur, as he dives into the revolutionary world of therapeutic video games. Discover how the FDA approved EndeavorRx, the first prescription video game for children with ADHD. Larkin discusses impressive trial results, comparing this innovative approach to traditional medication. He also explores its adaptability, safety concerns, and the potential for personalized treatment, sparking a conversation on the future of digital therapeutics in pediatric mental health.
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INSIGHT

Engaging and Adaptive Therapy

  • The video game therapeutic is designed to be enjoyable and entertaining.
  • It also iterates in real-time, adjusting to the player's engagement and learning.
INSIGHT

Rigorous Clinical Trial Design

  • The study used a randomized controlled trial (RCT) where researchers, families, and patients were blinded.
  • The intention-to-treat method included all participants in the analysis.
INSIGHT

Pre-Registration and Objective Measurement

  • The study was pre-registered, outlining methods and endpoints beforehand to prevent bias.
  • It used TOVA API, an objective measure of attention, aligning with ADHD core impairments.
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