Nuance Needed 105: Depression, Anxiety, and the Myth of the Chemical Imbalance
Mar 31, 2026
46:12
What if the entire “chemical imbalance” story about depression was oversimplified… and it’s actually keeping you stuck?
In conversation, we tackle:
- The 2022 study that “debunked” serotonin—and why everyone completely overreacted to it
- How Big Pharma accidentally sold us an oversimplified story (because it was easier to market)
- The anxiety → over-functioning → burnout → depression crash cycle (and why so many high-achievers are stuck in it)
- Why “just think positive” might actually be making your depression worse
- The brutal reality: the things that help depression are the exact opposite of what you feel like doing
- Why chasing happiness is setting you up to feel worse—and what to aim for instead
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