TED Radio Hour Special Delivery
Oct 29, 2021
Amir Nizar Zuabi, a theater director known for his poignant storytelling through puppetry, shares insights on using art to convey the refugee experience. Astrophysicist Erika Hamden discusses her innovative FIREBALL telescope, revealing the emotional journey of cosmic discovery. Kathryn Whitehead, a chemical engineer specializing in mRNA vaccines, emphasizes the importance of precise drug delivery technology. Lastly, Keller Rinaudo, CEO of Zipline, highlights the life-saving potential of drone logistics in medical supply distribution.
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Protecting mRNA
- mRNA, like a fragile vase, needs protection and an address for delivery.
- Scientists have developed lipid nanoparticles, the "shipping materials" for mRNA.
Lipid Nanoparticles
- mRNA is fragile and needs protection to reach cells without being destroyed.
- Lipid nanoparticles act as packaging, allowing mRNA to enter cells like a Trojan horse.
Nanoparticle Ingredients
- Lipid nanoparticles contain phospholipids, cholesterol, ionizable lipids, and PEG.
- These ingredients protect mRNA, enabling its use in vaccines and future disease treatments.