The Truth About Hollywood’s Favorite Anxiety Drug | Really? no, Really?

Hollywood’s latest “anxiety hack” isn’t a new miracle drug — it’s an old medication with a new spotlight. Jason Alexander and Peter Tilden dig into the celebrity buzz around beta blockers with Dr. Nasser Ghaemi, an academic psychiatrist and professor of psychiatry at Tufts University. They break down what beta blockers (like propranolol) actually do, why actors and musicians use them for performance anxiety, and the big catch: they can reduce symptoms without addressing the root cause. Dr. Ghaemi explains when “situational” use can make sense — and when it can backfire with side effects like low blood pressure, cognitive dulling, or added risk for people with asthma or diabetes. Along the way, Jason and Peter riff on Hollywood nerves, guest-star pressure on Seinfeld, and a wild story about “anxiety drugs in rivers” making salmon bolder — because of course it does. The episode lands on a bigger debate: quick-fix culture, rising anxiety in young people, and why AI therapy can’t replace a human clinician (yet).

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