Bloomberg Businessweek

Predicting Risk of Postpartum Depression

Mar 6, 2026
Dr. Lauren Osborne, a reproductive psychiatrist at Weill Cornell studying mental health around pregnancy. She discusses how common postpartum depression is and why it is often missed. She explores treatment options including new hormone-based drugs. She explains research on neuroactive steroid blood markers that might predict risk during late pregnancy and the importance of partner support.
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INSIGHT

PPD Is Common But Largely Untreated

  • Postpartum depression (PPD) affects about 15–20% of birthing people in industrialized countries.
  • Despite this high prevalence, only ~3% of women with PPD are treated to remission due to underdiagnosis and limited access to care.
INSIGHT

Research Gaps Drive Missed PPD Care

  • Women's health research has lagged, contributing to gaps in understanding and treating postpartum depression.
  • NIH only mandated female animals in studies in 2014, illustrating how recently research began including women systematically.
ADVICE

Deliver Proven Treatments Early And Accessibly

  • Offer evidence-based treatments early: psychotherapy, traditional antidepressants, and new hormone-based drugs.
  • Make access easier so available effective treatments actually reach postpartum people when needed.
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