The Neuro Experience

#347: Why Nitric Oxide is the Key to Heart and Brain Health | Dr. Nathan Bryan

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Jun 20, 2024
Guest
Nathan Bryan
Dr. Nathan Bryan discusses nitric oxide's role in heart and brain health, highlighting its decline with age and the link to diet. He explores the surprising connection between oral hygiene and nitric oxide levels. Topics include nutrient depletion in the standard diet, nitric oxide in mitochondrial function, and controversies surrounding nitrates in food.
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INSIGHT

Oral Bacteria Are A Nitric Oxide Source

  • An independent oral bacteria pathway converts dietary nitrate to nitrite and supports systemic nitric oxide and blood pressure regulation.
  • Disrupting the oral microbiome impairs this pathway and can rapidly raise blood pressure.
ADVICE

Stop Antiseptic Mouthwash For Blood Pressure

  • Avoid antiseptic mouthwash and fluoride toothpaste that destroy oral nitrate-reducing bacteria.
  • Stop using antiseptic mouthwash and blood pressure can normalize within days as the oral microbiome repopulates.
INSIGHT

Periodontal Dysbiosis Lowers Systemic NO

  • The oral systemic link includes dysbiosis-driven loss of beneficial NO-producing bacteria, not only translocation of pathogens.
  • Restoring commensal oral bacteria can reduce inflammation and cardiovascular risk.
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