
Sex With Emily How to Have Sex While On Antidepressants
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Mar 3, 2026 Discussion of why SSRIs and SNRIs can suppress desire and make orgasms difficult. Practical timing hacks and lifestyle tweaks to reduce sexual side effects without stopping medication. Overview of alternative treatments like TMS, ketamine, and psilocybin that may help people come off antidepressants. Strategies for couples who are both medicated to rebuild intimacy and arousal.
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Sarah's Antidepressant Sex Story
- Listener Sarah is on antidepressants and lost spontaneous desire and orgasm ease despite loving her partner.
- Emily compares reigniting sex to getting to the gym: getting started is hardest but usually leads to satisfaction.
How SSRIs Can Suppress Libido
- SSRIs increase serotonin which can suppress sexual desire and pleasure by impacting dopamine pathways.
- Emily explains the tradeoff: raising serotonin helps mood but often reduces dopamine-driven sexual stimulation.
Ask Your Doctor And Try Medication Alternatives
- Try lifestyle and medication alternatives like exercise, nutrition, switching to bupropion or mirtazapine, and discuss options with your doctor.
- Emily notes only ~20% of prescribers warn about sexual side effects, so proactively ask your clinician.






