Practical AI in Healthcare

S1, E15 - Adam Rodman: Rethinking Clinical Reasoning in the Age of AI

21 snips
Dec 7, 2025
Adam Rodman, physician, informatician, and historian of medicine, explores how large language models reshape clinical reasoning. He traces the arc from early diagnostic systems to GPT breakthroughs. He discusses workflow redesigns for clinician–AI collaboration, regulatory and liability gaps, patient-first AI agents, and early signals from urgent-care AI startups.
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INSIGHT

From Clinical Reasoning To Model Collaboration

  • Adam Rodman reframed his background as studying how clinicians think rather than building models.
  • He argues LLMs change how we must conceptualize clinical decision support and collaboration.
ANECDOTE

Testing LLMs Against Old Decision Tools

  • Rodman describes testing GPT models against classical clinical decision support benchmarks.
  • He found modern LLMs matched older systems like Isabel on contextual tasks with far less work.
INSIGHT

LLMs Break Old Evaluation Paradigms

  • Language models are powerful but multi‑functional and have unique failings like hallucination.
  • These traits force rethinking evaluation beyond traditional AUC/F1 metrics toward human-model interaction.
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