
Sigma Nutrition Radio #574: Microplastics & Health: What Do We Know? – Prof. Ian Mudway
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Aug 26, 2025 Join Professor Ian Mudway, an environmental toxicologist from Imperial College London, as he dives into the pressing issue of microplastics in our environment and bodies. He discusses their alarming prevalence in food and air and the complexities surrounding their health implications. The conversation balances public fascination with scientific evidence, tackling misconceptions and the role of media in shaping perceptions. Mudway emphasizes the need for clear communication and research, urging a broader view of environmental health priorities.
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Plymouth Research Sparked The Field
- Richard Thompson coined 'microplastic' and showed plastics increased in archived algae from the 1950s onward.
- He also fed particles to filter feeders to demonstrate ingestion and trophic transfer.
Detection ≠ Dose Or Harm
- Studies find microplastics in stool and occasionally in tissues and blood, but detection methods vary widely.
- Mudway emphasizes presence alone doesn't quantify dose or prove health harm without accurate measurement.
Measurement Challenges Are Central
- Current analytical methods can detect larger plastics but struggle with the <1 µm sizes most relevant for human uptake.
- Mudway warns many tissue reports may reflect measurement uncertainty or contamination during sampling.
