How I Doctor with Dr. Graham Walker

Move Over LLMS! AI Legends Yann LeCun and Alex LeBrun Debut AMI Labs' Bold Ambitions for World Models in Healthcare

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Feb 12, 2026
Yann LeCun, Turing Award–winning deep learning pioneer, and Alex LeBrun, entrepreneur and CEO building clinical AI tools, discuss world models for healthcare. They explore why next-word LLMs fall short. They debate patient simulation, sensor-rich data over text, reliability needs beyond 80% accuracy, and practical near-term wins like documentation and medical coding.
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INSIGHT

World Models Enable Planning Not Just Prediction

  • World models simulate future states from actions, enabling planning rather than token prediction.
  • Yann LeCun argues LLMs predict next tokens blindly, while world models imagine consequences to plan robustly.
INSIGHT

Sensor Data Outweighs Text For World Learning

  • Real-world sensor data vastly exceeds text in quantity and richness for learning dynamics.
  • Yann LeCun highlights vision and multi-sensory inputs as essential for building human-like models.
INSIGHT

Doctors Use Mental Patient Models To Plan Care

  • Clinicians run internal patient models to imagine treatment outcomes and sequences.
  • Yann LeCun suggests AI should replicate this internal simulation to predict effects of interventions.
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