The Neuro Experience

Expert Urologist Reveals the Hormone Making Women Look 10x Younger | Dr. Kelly Casperson

Jan 27, 2026
Dr. Kelly Casperson, a board-certified urologic surgeon and women’s health advocate, explains hormonal changes in perimenopause and menopause. She discusses why UTIs increase after menopause, how vaginal versus systemic estrogen work, and the link between estrogen receptors and brain aging. They also cover HRT basics, compounding pharmacies, and why women should reclaim control of their health.
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ANECDOTE

Career Shift Triggered By One Patient

  • A patient crying about sexual health sparked Kelly Casperson's shift to focus on women's sexual health.
  • She realized men aren't dismissed for libido issues the way women often are, which framed her equality mission.
INSIGHT

Estrogen Protects Vaginal Microbiome

  • Estrogen maintains a healthy vaginal microbiome by supporting lactobacillus that produce lactic acid.
  • Losing estrogen raises UTI risk because the vagina becomes less acidic and lets stool bacteria reach the bladder.
ADVICE

Use Local Vaginal Estrogen Regularly

  • Use low-dose local vaginal estrogen to re-acidify the vagina and reduce recurrent UTIs and sexual pain.
  • Apply typical regimens (e.g., twice weekly) and continue long-term; stopping reverses benefits.
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