Intelligence Squared

Is There a Crisis of Overdiagnosis in Modern Medicine? With Dr Suzanne O’Sullivan

18 snips
Apr 12, 2026
Suzanne O’Sullivan, a consultant neurologist and writer, explores the rise in diagnoses and whether everyday life and normal variations are being medicalized. She discusses when labels help or harm, the pitfalls of testing and screening, the role of genetics and wearables, and how to decide if a diagnosis actually delivers meaningful support.
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INSIGHT

Diagnosis Balances Benefit And Harm

  • Diagnosis can bring benefits and harms depending on severity of symptoms.
  • Suzanne O'Sullivan noticed many young patients with long lists of diagnoses who did not get better, prompting concern about overdiagnosis.
ANECDOTE

Valentina's Two Decades Without A Genetic Label

  • Valentina delayed Huntington's genetic testing for 20 years to preserve hope and normal life while pregnant and raising children.
  • When she finally tested, very disabled and convinced she'd be positive, the result was negative, illustrating how labels change symptom interpretation.
INSIGHT

Early Detection Creates False Positives

  • Early detection isn't always beneficial because many detected abnormalities never progress to harmful disease.
  • Suzanne uses prostate cancer screening data to show many men have abnormal cells that won't become life‑threatening but get treated because we can't yet distinguish which will.
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