
Anderson Cooper 360 Sheriff: “We Have DNA” In Guthrie Case
Feb 14, 2026
Andrew McCabe, former FBI deputy director with decades leading major federal investigations, joins to explain federal-local cooperation. He discusses DNA findings tied to the Guthrie house and how analysis and genealogy tools are used. Conversation covers camera and video searches, managing tip surges, and the stresses of high-profile probes.
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Unknown DNA Could Be A Breakthrough
- Investigators recovered DNA at Nancy Guthrie's home that doesn't match her or known household contributors.
- Officials are testing that DNA and gloves found up to 10 miles away to determine links to the crime.
Check And Share Local Camera Footage
- Law enforcement urged residents to check and share camera footage within a two-mile radius to help identify the suspect's vehicle or route.
- Investigators are working to extract video from interior cameras and hope it yields additional angles or accomplice evidence.
Unknown DNA Still Provides Paths Forward
- DNA with no match in criminal databases is still useful once you have a suspect to compare against or can attempt genealogy searches.
- Investigators may use commercial DNA databases for familial leads, but it's unclear if that's happening here.

