Skin Anarchy Hormones, Oxytocin, and Aging with Dr. Sabrina Fabi of XOMD Skincare
In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with double board-certified dermatologist Dr. Sabrina Fabi to examine how hormonal signaling actively shapes skin resilience, recovery, and structural integrity. This conversation moves beyond trend-driven skincare and into the biology that determines how skin functions at every stage of life.
Dr. Fabi emphasizes that skin constantly responds to hormonal shifts. Changes in progesterone, estrogen, testosterone, and neurohormones influence collagen production, barrier strength, inflammation, muscle tone, and healing capacity. Aging reflects signaling patterns — not just the passage of time. When hormones fluctuate, skin behavior changes.
A central focus of the discussion is oxytocin. While most people associate oxytocin with bonding and mood, Dr. Fabi explains that skin contains oxytocin receptors that participate in local repair and inflammatory signaling. That neuroendocrine connection reframes how we think about resilience. The brain and skin communicate continuously, and hormonal signaling drives that dialogue.
Dr. Fabi applies this signaling-first framework directly through XOMD. Instead of topically applying exogenous hormones, she built XOMD around activating intrinsic pathways that support recovery and tissue strength. The focus remains on optimizing communication within the skin rather than overwhelming it with isolated actives.
Throughout the episode, she challenges casual aesthetic culture and reinforces the importance of individualized, long-term planning. Hormones shape anatomy, metabolism, and tissue quality — treatment strategies must reflect that complexity.
Listen to the full episode to hear Dr. Sabrina Fabi break down hormonal biology, oxytocin science, and how XOMD advances a more intelligent approach to skin resilience.
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