AI Snips
Chapters
Transcript
Episode notes
Early Dialysis Trials Miss Volume Nuance
- Early versus delayed dialysis shows no clear outcome benefit in trials except for poorly defined volume indications.
- Volume assessment is subjective, so trials struggle to capture benefits of early volume control.
Prefer CRRT For Hemodynamically Unstable Patients
- Choose CRRT for hypotensive, volume-managed ICU patients needing gradual fluid control.
- Use intermittent HD only for urgent, fast solute removal or when hemodynamics permit.
Effluent Rate Is The Key CRRT Dose
- CRRT dosing is expressed as effluent (mL/kg/hr) and targets ~20–25 mL/kg/hr.
- Centers often prescribe ~25–30 mL/kg/hr to account for downtime and clotting.