Heading into Week 6, Tim Murray opens up the podcast with a "sandwich" spot this weekend and a shoutout to a podcast listener's prediction from the summer.

Tim then welcomed Wes Reynolds to the podcast for his weekly visit. Tim & Wes discussed Indiana's 20-15 win over Iowa and took a quick lookahead at Indiana at Oregon next weekend. Tim & Wes ran through situational spots for this weekend including...

-Illinois at Purdue

-Washington at Maryland

-Penn State at UCLA

-UVA at Louisville

-Kent State at Oklahoma

-Iowa State at Cincinnati

Lastly, Tim brought on Brett Ciancia of Pick Six Previews. Tim & Brett discussed the Pick Six Plus game grader function and discussed the top graded games of the 2025 season. Looking back, Brett recapped the Oregon 30-24 win over Penn State. How much did that change his perspective on both teams? Tim & Brett previewed the upcoming weekend including...

-Vanderbilt at Alabama

-Miami at Florida State

-Iowa State at Cincinnati

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Week 6 Wednesdays with Wes Reynolds & Brett Ciancia (@PickSixPreviews)