The Pitt Podcast 5:00 P.M. with Alexandra Metz and Michael Hissrich
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Mar 20, 2026 Michael Hissrich, executive producer who oversees production and story decisions. Alexandra Metz, actor who plays Dr. Yolanda Garcia and discusses character prep and relationships. They discuss Pittsburgh as the show's setting, the choice to tackle ICE and healthcare tensions, and the chemistry and dynamics between Garcia and Santos.
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Xylazine 'Trank' Causes Necrosis And Is Not Reversed By Narcan
- Xylazine causes skin necrosis and is not reversed by naloxone, complicating overdose care.
- Alok Patel explains xylazine is a veterinary tranquilizer called trank that can cause injection-site necrosis and won't respond to Narcan.
Actor Training And Doctor Friends Shaped Dr Garcia
- Alexandra Metz drew on Brown's liberal medical education program and physician friends to shape Dr. Garcia's realism.
- Metz says friends from that cohort, now top doctors, inform her portrayal and give scene-level guidance.
Surgeons Compartmentalize To Survive High Stress
- Surgeons often compartmentalize to cope with constant trauma and cortisol exposure.
- Alexandra Metz cites a sports psychologist and says compartmentalizing preserves performance and personal wellbeing for surgeons.