Into the Impossible With Brian Keating

Science Journalist: They Called Him Crazy Then The Death Rate Went to Zero

Mar 29, 2026
Matt Kaplan, science journalist and trained paleontologist at The Economist, tours the missteps of modern science. He tells the Semmelweis handwashing saga and why infection rates plunged. He contrasts Karikó's protection with Semmelweis's fate. He dives into the replication crisis, funding pressures, gatekeeping, and how journalism often mangles scientific process.
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INSIGHT

Pandemic Revealed Science's Messy Process

  • The pandemic exposed science's messy, iterative process to the public, causing surprise when scientists disagreed or changed conclusions.
  • Matt Kaplan argues journalists must explain how science is made, not just report final claims, to preserve public trust.
ANECDOTE

Semmelweis Clean Hands Cut Deaths To Zero

  • Ignaz Semmelweis reduced puerperal fever from 21% to zero by forcing doctors to wash hands with chlorine after autopsies.
  • He documented ward-by-ward rates, tried alternate hypotheses, found smells of corpses on his hands, and his handwashing intervention immediately collapsed infections.
INSIGHT

Shelter Determines Scientific Survival

  • Personal shelter and allies can determine whether a persecuted innovator survives; Katalin Karikó had mentors who shielded her work.
  • Kaplan contrasts Karikó's decade-long protection from colleagues with Semmelweis's social isolation and exile.
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