The Funk'tional Nutrition Podcast The Liver-Hormone Link: How to Detox Without the Gimmicks (And the Products I Use to Support It) | Ep 359
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May 6, 2025 Nicole Antes, a functional dietitian and liver health expert, dives into the often overlooked connection between the liver and hormones. She reveals how everyday toxins, like fragrances and cookware materials, impact hormonal health. Listeners learn about the rise of non-alcoholic fatty liver disease and practical, non-faddish detox strategies, including dietary changes and liver-supporting supplements. Nicole also emphasizes the importance of daily bowel movements for hormone elimination and offers smart swaps for a healthier, non-toxic lifestyle.
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Genetics Affect Estrogen Detox
- Genetic mutations like COMT and MTHFR impact estrogen detoxification in liver phase one and two.
- Low COMT or impaired methylation from MTHFR variants can lead to poor estrogen clearance and hormonal symptoms.
Supplements for Liver Support
- Support low methylation and estrogen dominance symptoms with methylated B vitamins, SAMe, and NAC supplements.
- NAC boosts glutathione, a key antioxidant critical for liver detox and estrogen clearance.
Boost Gut for Estrogen Detox
- Support gut health and estrogen detox by balancing gut bacteria to reduce beta-glucuronidase enzyme activity.
- Elevated beta-glucuronidase causes estrogen reabsorption, worsening estrogen dominance symptoms like heavy periods and PMS.