Ageless Future How Your Immune System Drives Aging: A Precision-Based Approach to Longevity with Dr. Natalia Mitin
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Sep 17, 2025 Dr. Natalia Mitin, an immunologist and founder of SapereX, dives into the intricate link between the immune system and aging. She reveals how immunosenescence impacts organ function and why precise diagnostics are crucial for longevity. Discussing her breakthrough SapereX test, she highlights how T-cell gene expression offers actionable insights for personalized therapies. Natalia cautions against relying on traditional biomarkers and emphasizes that true longevity stems from tailored interventions that address individual biological needs.
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Measure Close To The Biology For Precision
- Measuring direct, stable markers close to the biology reduces noise and increases clinical usefulness of tests.
- SapereX isolates T cells and reads gene expression to give a precise, stable immune-age signal.
Test Before Stacking Interventions
- Test before stacking longevity therapies so you know which lever to pull and avoid harmful stacks.
- Track targeted biomarkers to confirm benefit and stop ineffective or damaging interventions.
Surrogates Can Mislead Senescence Assessment
- Surrogate markers (e.g., telomeres, X-Gal staining) often give noisy or incomplete pictures of senescence.
- Direct functional measures of T-cell gene expression reveal actionable immune aging signals.