
KQED's Forum How to Be a 'Super Ager' With Dr. Eric Topol
Jan 16, 2026
Dr. Eric Topol, a leading cardiologist and genetic researcher, shares his insights on aging gracefully and maximizing longevity. He emphasizes that lifestyle choices, like exercise and diet, significantly outweigh genetics. The discussion explores immune health, linking it to aging, and the impact of social engagement and activities like dancing on mental well-being. Topol also highlights the role of AI in predicting health outcomes, the importance of balance and strength training, and the potential of fasting for weight management. His practical advice aims to inspire everyone to become 'super agers'.
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Choose Safe, Effective Exercise
- Do low-impact aerobic and strength workouts like deep-water aerobics if available to protect joints and build fitness.
- Avoid unproven practices like extreme cold plunges that lack evidence and may harm people with heart disease.
Vagus Nerve Modulates Inflammation
- The vagus nerve links gut, brain, and immune signaling and can be stimulated to reduce inflammation.
- Neuromodulation of the vagus nerve has shown benefit in rheumatoid arthritis trials.
Dance Beats Drugs For Depression
- Use dance or other physical activity to treat and prevent depression; dance outperformed SSRIs in reviews.
- Prioritize movement types that combine physical, cognitive, and social engagement.




